-Administer by deep intramuscular injection only into the neck area, using aseptic technique. The dosage and frequency of therapy required depends upon the clinical condition and copper status of the animal, as assessed by serum levels before and after treatment and after consultation with the veterinary surgeon. This is particularly relevant to sheep as they are sensitive to copper toxicity. The copper status on farms may change from year to year; it is therefore recommended that random samples of serum are periodically checked to see if the deficiency still exists.